Back إروين روز Arabic اروين روز ARZ اروین روز AZB Ірвін Роўз Byelorussian Ъруин Роуз Bulgarian আরউইন রোজ Bengali/Bangla Irwin Rose Catalan Irwin Rose Czech Irwin Rose Danish Irwin Rose German
Irwin Rose | |
|---|---|
 Irwin Rose, c. 2000 | |
| Born | Irwin Allan Rose July 16, 1926 Brooklyn, New York, U.S. |
| Died | June 2, 2015 (aged 88) Deerfield, Massachusetts, U.S. |
| Alma mater | University of Chicago (BS, PhD) NYU (postdoc) |
| Known for | Ubiquitin-mediated protein degradation |
| Spouse | Zelda Budenstein[1] |
| Children | 4[1] |
| Awards | Nobel Prize in Chemistry (2004) |
| Scientific career | |
| Fields | Biology |
| Institutions | |
| Thesis | Studies on the Biochemical Synthesis of Nucleic Acids (1952) |
| Doctoral advisor | Bernard S. Schweigert |
Irwin Allan Rose (July 16, 1926 – June 2, 2015) was an American biologist. Along with Aaron Ciechanover and Avram Hershko, he was awarded the 2004 Nobel Prize in Chemistry for the discovery of ubiquitin-mediated protein degradation.[2][1][3]
- ^ a b c Rose, I (11 August 2005). "Early work on the ubiquitin proteasome system, an interview with Irwin Rose". Cell Death & Differentiation. 12 (9). Springer Science and Business Media LLC: 1162–1166. doi:10.1038/sj.cdd.4401700. ISSN 1350-9047. PMID 16094392.
- ^ Wilkinson, Keith; Hershko, Avram (2015). "Irwin Allan Rose (1926–2015) Established role of ubiquitin in the destruction of cellular proteins". Nature. 523 (7562): 532. doi:10.1038/523532a. ISSN 0028-0836. PMID 26223618.
- ^ Hershko, A.; Ciechanover, A.; Rose, I.A. (1979), "Resolution of the ATP-dependent proteolytic system from reticulocytes: a component that interacts with ATP", Proc. Natl. Acad. Sci. USA, 76 (7): 3107–3110, Bibcode:1979PNAS...76.3107H, doi:10.1073/pnas.76.7.3107, PMC 383772, PMID 290989.
© MMXXIII Rich X Search. We shall prevail. All rights reserved. Rich X Search